Waterfall plot Oncolines® drug sensitivity

The waterfall plot ranks the 102 cancer cell lines from the Oncolines® panel on relative sensitivity to dabrafenib in proliferation assays.
Cell lines expressing mutant BRAF are indicated in red (all have V600E mutation, except for BxPC-3); wild-type cell lines are indicated in blue.

Hover over the waterfall plot to show the name of each cell line and the IC50 value (in nM).

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RKOCOLO 205LS411NSW872RPMI-7951COLO 829G-361DU4475A-375ES-25637ACHNBxPC-3A-498A-704DaoyHT-1080AU565MeWoOVCAR-3769-PDLD-1DU145HCT 116Hs 578TSW900NCI-H82NCI-H460SW982NCC-ITT24RS4;11KG-1Jurkat E6.1HCT 15BT-549JARKLECCRF-CEM786-OPA-1DBSRKATO IIIRDA-204TCCSUPVA-ES-BJU-118MGA-427SU-DHL-6AN3-CAFaDuA-549LNCaP clone FGCRL95-2SW480HuTu 80SW48SK-N-ASU-87MG ATCCLoVoKu812A-172A-388AsPC-1BT-20C-33 ACAL-27CCF-STTG1DoTc2 4510HL-60Hs 746.THs 766THTJ82K-562LS174TMCF-7MG-63MIA PaCa-2MOLT-4NCI-H661PC-3PFSK-1RLRT-4SHP-77Rh30SK-N-FISNU-5SNU-C2BSU-DHL-1SUP-T1SW620SW626SW837T98GTHP-1TTU2OS−2−1.5−1−0.500.5
BRAF mutantBRAF wild-type10logIC​50 - ​10logIC​50, averagedabrafenib