List of Kinases for Activity Screening

Table – Kinases for Activity Screening

QuickScout™ Kinase Activity Assays

Target Name Group Available Services Source
(Carna Catalog Number)
(Mobility Shift Assay, IMAP™) Pre-selected Panel
ABL (ABL1) TK Km bin. 1 mM Preincubation TK 08-001
ABL (ABL1) [E255K] TK Km_bin. 1 mM Preincubation 08-094
ABL (ABL1) [T315I] TK Km bin. 1 mM Preincubation 08-093
ACK (TNK2) TK Km bin. 1 mM 08-196
AKT1 STK Km bin. 1 mM Preincubation STK 01-101
AKT2 STK Km bin. Preincubation 01-102
AKT3 STK Km bin. Preincubation 01-103
ALK TK Km bin. 1 mM Preincubation 08-518
ALK [T1151_L1152insT] TK Km bin. 1 mM 08-539
ALK [C1156Y] TK Km bin. 1 mM Preincubation 08-530
ALK [F1174L] TK Km bin. 1 mM Preincubation 08-519
ALK [L1196M] TK Km bin. 1 mM Preincubation 08-529
ALK [G1202R] TK Km bin. 1 mM Preincubation 08-544
ALK [G1269A] TK Km bin. 1 mM Preincubation 08-537
ALK [R1275Q] TK Km bin. 1 mM Preincubation 08-520
AMPKα1/β1/γ1 (PRKAA1/B1/G1) STK Km bin. 1 mM Preincubation STK 02-113
AMPKα2/β1/γ1 (PRKAA2/B1/G1) STK Km bin. Preincubation 02-114
ARG (ABL2) TK Km bin. 1 mM Preincubation 08-102
AurA (AURKA) STK Km bin. 1 mM Preincubation STK Cell_Cycle 05-101
AurA (AURKA)/TPX2 STK Km bin. Preincubation 05-186
AurB (AURKB)/INCENP STK Km bin. 1 mM Preincubation Cell Cycle 05-102
AurC (AURKC) STK Km bin. 1 mM Cell Cycle 05-103
AXL TK Km bin. 1 mM 08-107
BLK TK Km bin. 1 mM 08-164
BMX TK Km bin. 1 mM Preincubation 08-179
BRAF STK 1 mM (Cascade) MAPK (Cascade) 09-122
BRAF [V600E] STK 1 mM (Cascade) 09-144
BRK (PTK6) TK Km bin. 1 mM 08-165
BRSK1 STK Km bin. 1 mM Preincubation 02-115
BRSK2 STK Km bin. Preincubation Cell Cycle 02-116
BTK TK Km bin. 1 mM 08-180
BTK [C481S] TK Km bin. 1 mM 08-547
BUB1/BUB3 STK Km bin. Preincubation 05-187
CaMK1α (CAMK1) STK Km bin. 1 mM 02-104
CaMK1δ (CAMK1D) STK Km bin. 02-106
CaMK2α (CAMK2A) STK Km bin. Preincubation 02-109
CaMK2β (CAMK2B) STK Km bin. Preincubation 02-110
CaMK2γ (CAMK2G) STK Km bin. Preincubation 02-112
CaMK2δ (CAMK2D) STK Km bin. Preincubation 02-111
CaMK4 STK Km bin. 1 mM Preincubation STK 02-108
CDC7/ASK STK Km bin. 1 mM Cell Cycle 05-109
CDK1 (CDC2)/CycB1 STK Km bin. 1 mM Preincubation Cell Cycle 04-102
CDK2/CycA2 STK Km bin. 1 mM Preincubation STK Cell Cycle 04-103
CDK2/CycE1 STK Km bin. 1 mM Preincubation Cell Cycle 04-165
CDK3/CycE1 STK Km bin. 1 mM Preincubation Cell Cycle 04-104
CDK4/CycD3 STK Km bin. 1 mM Cell Cycle 04-105
CDK5/p25 STK Km bin. 1 mM Preincubation 04-106
CDK6/CycD3 STK Km bin. 1 mM Cell Cycle 04-107
CDK7/CycH/MAT1 STK Km bin. 1 mM Cell Cycle 04-108
CDK9/CycT1 STK Km bin. 1 mM Cell Cycle 04-110
CGK2 (PRKG2) STK Km bin. Preincubation 01-143
CHK1 (CHEK1) STK Km bin. 1 mM Preincubation STK Cell Cycle 02-117
CHK2 (CHEK2) STK Km bin. 1 mM Preincubation Cell Cycle 02-162
CK1α (CSNK1A1) STK Km bin. 1 mM 03-101
CK1γ2 (CSNK1G1) STK Km bin. Preincubation 03-105
CK1γ2 (CSNK1G2) STK Km bin. Preincubation 03-106
CK1γ3 (CSNK1G3) STK Km bin. Preincubation 03-107
CK1δ (CSNK1D) STK Km bin. Preincubation 03-103
CK1ε (CSNK1E) STK Km bin. 1 mM STK 03-104
CK2α1/β (CSNK2A1/B) STK Km bin. 1 mM Preincubation Cell Cycle 05-184
CK2α2/β (CSNK2A2/B) STK Km bin. Preincubation Cell Cycle 05-185
CLK1 STK Km bin. 1 mM Preincubation 04-126
CLK2 STK Km bin. 1 mM Preincubation 04-127
CLK3 STK Km bin. Preincubation 04-128
COT (MAP3K8) STK 1 mM (Cascade) MAPK (Cascade) 07-301
CRIK (CIT) STK Km bin. 01-104
CSK TK Km bin. 1 mM TK 08-111
DAPK1 STK Km bin. 1 mM Preincubation STK 02-134
DCAMKL2 STK Km bin. 02-140
DDR1 TK Km bin. 1 mM 08-113
DDR2 TK Km bin. 1 mM 08-114
DLK (MAP3K12) STK 1 mM (Cascade) MAPK (Cascade) 09-111
DYRK1A STK Km bin. 1 mM Preincubation 04-130
DYRK1B STK Km bin. 1 mM Preincubation STK 04-131
DYRK2 STK Km bin. Preincubation 04-132
DYRK3 STK Km bin. Preincubation 04-133
EEF2K STK Km bin. 10-113
EGFR TK Km bin. 1 mM Preincubation TK 08-115
EGFR [d746-750] TK Km bin. 1 mM Preincubation 08-527
EGFR [d746-750/T790M] TK Km bin. 1 mM 08-528
EGFR [d746-750/T790M/C797S] TK Km bin. 1 mM 08-565
EGFR [d746-750/C797S] TK Km bin. 1 mM Preincubation 08-564
EGFR[D770_N771insNPG] TK Km bin. 1 mM 08-553
EGFR [T790M] TK Km bin. 1 mM Preincubation 08-194
EGFR [T790M/L858R] TK Km bin. 1 mM Preincubation 08-510
EGFR [T790M/C797S/L858R] TK 1 mM 08-510
EGFR [C797S/L858R] TK Km bin. 1 mM 08-510
EGFR [L858R] TK Km bin. 1 mM Preincubation 08-502
EGFR [L861Q] TK Km bin. 1 mM Preincubation 08-513
EML4-ALK TK Km bin. 1 mM 08-516
EPHA1 TK Km bin. 1 mM Preincubation 08-119
EPHA2 TK Km bin. 1 mM Preincubation TK 08-121
EPHA3 TK Km bin. 1 mM Preincubation 08-122
EPHA4 TK Km bin. 1 mM Preincubation 08-123
EPHA5 TK Km bin. 1 mM Preincubation 08-124
EPHA6 TK Km bin. 1 mM Preincubation 08-125
EPHA7 TK Km bin. 1 mM Preincubation 08-126
EPHA8 TK Km bin. 1 mM Preincubation 08-127
EPHB1 TK Km bin. 1 mM Preincubation 08-128
EPHB2 TK Km bin. 1 mM Preincubation 08-129
EPHB3 TK Km bin. 1 mM Preincubation 08-130
EPHB4 TK Km bin. 1 mM Preincubation TK 08-131
Erk1 (MAPK3) STK Km bin. 1 mM Preincubation MAPK (Cascade) 04-142
Erk2 (MAPK1) STK Km bin. 1 mM Preincubation STK MAPK (Cascade) 04-143
Erk5 (MAPK7) STK Km bin. 1 mM MAPK (Cascade) 04-146
FAK (PTK2) TK Km bin. 1 mM 08-137
FER TK Km bin. 1 mM Preincubation 08-139
FES TK Km bin. 1 mM Preincubation 08-140
FGFR1 TK Km bin. 1 mM Preincubation TK 08-133
FGFR1 [V561M] TK Km bin. 1 mM 08-536
FGFR2 TK Km bin. 1 mM Preincubation 08-134
FGFR2 [V564I] TK Km bin. 1 mM Preincubation 08-546
FGFR3 TK Km bin. 1 mM 08-135
FGFR3 [V555L] TK Km bin. 1 mM 08-548
FGFR3 [K650E] TK Km bin. 1 mM 08-501
FGFR3 [K650M] TK Km bin. 1 mM 08-199
FGFR3 [V555M] TK Km bin. 1 mM 08-543
FGFR4 TK Km bin. 1 mM Preincubation 08-136
FGFR4 [N535K] TK Km bin. 1 mM 08-524
FGFR4 [V550E] TK Km bin. 1 mM 08-525
FGFR4 [V550L] TK Km bin. 1 mM Preincubation 08-526
FGR TK Km bin. 1 mM Preincubation 08-166
FLT1 TK Km bin. 1 mM Preincubation 08-189
FLT3 TK Km bin. 1 mM TK 08-154
FLT4 TK Km bin. 1 mM Preincubation 08-190
FMS (CSF1R) TK Km bin. 1 mM 08-155
FRK TK Km bin. 1 mM Preincubation 08-167
FYN [isoform a] TK Km bin. 1 mM 08-168
FYN [isoform b] TK Km bin. 1 mM 08-531
GSK3α (GSK3A) STK Km bin. 1 mM Preincubation 04-140
GSK3β (GSK3B) STK Km bin. 1 mM Preincubation STK Cell Cycle 04-141
Haspin (GSG2) STK Km bin. Preincubation 05-111
HCK TK Km bin. 1 mM 08-169
HER2 (ERBB2) TK Km bin. 1 mM 08-016
HER4 (ERBB4) TK Km bin. 1 mM Preincubation 08-118
HGK (MAP4K4) STK Km bin. 1 mM STK 07-137
HIPK1 STK Km bin. Preincubation 04-135
HIPK2 STK Km bin. Preincubation 04-136
HIPK3 STK Km bin. Preincubation 04-137
HIPK4 STK Km bin. 1 mM Preincubation 04-138
HPK1 (MAP4K1) STK Km bin. 07-410
IGF1R TK Km bin. 1 mM Preincubation TK 08-141
IKKα (CHUK) STK Km bin. 05-112
IKKβ (IKBKB) STK Km bin. 1 mM Preincubation STK 05-084
IKKε (IKBKE) STK Km bin. 05-114
INSR TK Km bin. 1 mM Preincubation 08-142
IRAK1 STK Km bin. 09-101
IRAK4 STK Km bin. 1 mM STK 09-145
IRR (INSRR) TK Km bin. 1 mM 08-143
ITK TK Km bin. 1 mM TK 08-181
JAK1 TK Km bin. 1 mM 08-144
JAK2 TK Km bin. 1 mM Preincubation 08-045
JAK3 TK Km bin. 1 mM Preincubation TK 08-046
JNK1 (MAPK8) STK Km bin. 1 mM Preincubation MAPK (Cascade) 04-163
JNK2 (MAPK9) STK Km bin. 1 mM Preincubation STK MAPK (Cascade) 04-164
JNK3 (MAPK10) STK Km bin. 1 mM Preincubation MAPK (Cascade) 04-150
KDR (VEGFR2) TK Km bin. 1 mM Preincubation TK 08-191
KIT TK Km bin. 1 mM 08-156
KIT [V560G] TK Km bin. 1 mM 08-504
KIT [V654A] TK Km bin. 1 mM 08-511
KIT [T670I] TK Km bin. 1 mM 08-195
KIT [D816E] TK Km bin. 1 mM 08-541
KIT [D816V] TK Km bin. 1 mM 08-505
KIT [D816Y] TK Km bin. 1 mM 08-534
LATS1/MOBKL1A STK Km bin. 01-523
LATS2/MOBKL1A STK Km bin. 01-524
LCK TK Km bin. 1 mM Preincubation TK 08-170
LOK (STK10) STK Km bin. 07-315
LTK TK Km bin. 1 mM 08-106
LYNa TK Km bin. 1 mM Preincubation 08-171
LYNb TK Km bin. 1 mM Preincubation 08-172
MAP2K1 STK 1 mM (Cascade) MAPK (Cascade) 07-141
MAP2K2 STK 1 mM (Cascade) MAPK (Cascade) 07-142
MAP2K3 STK 1 mM (Cascade) MAPK (Cascade) 07-143
MAP2K4 STK 1 mM (Cascade) MAPK (Cascade) 07-144
MAP2K5 STK 1 mM (Cascade) MAPK (Cascade) 07-145
MAP2K6 STK 1 mM (Cascade) MAPK (Cascade) 07-146
MAP2K7 STK 1 mM (Cascade) MAPK (Cascade) 07-148
MAP3K1 STK 1 mM (Cascade) MAPK (Cascade) 07-103
MAP3K2 STK 1 mM (Cascade) MAPK (Cascade) 07-104
MAP3K3 STK 1 mM (Cascade) MAPK (Cascade) 07-105
MAP3K4 STK 1 mM (Cascade) MAPK (Cascade) 07-106
MAP3K5 STK 1 mM (Cascade) MAPK (Cascade) 07-107
MAP4K2 STK Km bin. 07-111
MAPKAPK2 STK Km bin. 1 mM Preincubation STK 02-142
MAPKAPK3 STK Km bin. Preincubation 02-143
MAPKAPK5 STK Km bin. Preincubation 02-144
MARK1 STK Km bin. Preincubation 02-120
MARK2 STK Km bin. Preincubation 02-121
MARK3 STK Km bin. Preincubation 02-122
MARK4 STK Km bin. Preincubation 02-123
MELK STK Km bin. 02-124
MER (MERTK) TK Km bin. 1 mM Preincubation 08-108
MET TK Km bin. 1 mM Preincubation TK 08-151
MET [D1228H] TK Km bin. 1 mM Preincubation 08-540
MET [Y1235D] TK Km bin. 1 mM Preincubation 08-198
MET [M1250T] TK Km bin. 1 mM Preincubation 08-545
MINK (MINK1) STK Km bin. 1 mM 07-139
MLK1 (MAP3K9) STK 1 mM (Cascade) MAPK (Cascade) 09-115
MLK2 (MAP3K10) STK 1 mM (Cascade) MAPK (Cascade) 09-116
MLK3 (MAP3K11) STK 1 mM (Cascade) MAPK (Cascade) 09-017
MNK1 (MKNK1) STK Km bin. Preincubation 02-145
MNK2 (MKNK2) STK Km bin. Preincubation 02-146
MOS STK 1 mM (Cascade) MAPK (Cascade) 05-118
MRCKα (CDC42BPA) STK Km bin. 01-107
MRCKβ (CDC42BPB) STK Km bin. 01-108
MSK1 (RPS6KA5) STK Km bin. Preincubation 01-147
MSK2 (RPS6KA4) STK Km bin. 01-148
MSSK1 (STK23) STK Km bin. 04-159
MST1 (STK4) STK Km bin. 1 mM STK 07-116
MST2 (STK3) STK Km bin. 07-117
MST3 (STK24) STK Km bin. 07-118
MST4 STK Km bin. 07-119
MUSK TK Km bin. 1 mM 08-153
NDR1 (STK38) STK Km bin. 01-125
NDR2 (STK38L) STK Km bin. 01-126
NEK1 STK Km bin. 1 mM Cell Cycle 05-123
NEK2 STK Km bin. 1 mM Preincubation STK Cell Cycle 05-226
NEK4 STK Km bin. Preincubation 05-128
NEK6 STK Km bin. 1 mM Cell Cycle 05-130
NEK7 STK Km bin. 1 mM Cell Cycle 05-131
NEK9 STK Km bin. 1 mM Cell Cycle 05-133
NIM1K (MGC42105) STK Km bin. Preincubation 02-175
NPM1-ALK TK Km bin. 1 mM Preincubation 08-517
NuaK1 (ARK5) STK Km bin. Preincubation 02-126
NuaK2 STK Km bin. Preincubation 02-127
p38α (MAPK14) STK Km bin. 1 mM Preincubation STK MAPK (Cascade) Cell Cycle 04-152
p38β (MAPK11) STK Km bin. 1 mM Preincubation MAPK (Cascade) 04-153
p38γ (MAPK12) STK Km bin. 1 mM Preincubation MAPK (Cascade) 04-155
p38δ (MAPK13) STK Km bin. 1 mM Preincubation MAPK (Cascade) 04-154
p70S6K (RPS6KB1) STK Km bin. 1 mM Preincubation STK Cell Cycle 01-154
p70S6Kβ (RPS6KB2) STK Km bin. Preincubation 01-155
PAK1 STK Km bin. Preincubation 07-123
PAK2 STK Km bin. 1 mM Preincubation STK 07-124
PAK4 STK Km bin. 07-126
PAK5 (PAK7) STK Km bin. Preincubation 07-127
PAK6 STK Km bin. 07-128
PASK STK Km bin. 02-128
PBK STK Km bin. 1 mM STK 05-168
PDGFRα (PDGFRA) TK Km bin. 1 mM Preincubation TK 08-157
PDGFRα (PDGFRA) [V561D] TK Km bin. 1 mM Preincubation 08-507
PDGFRα (PDGFRA) [T674I] TK Km bin. 1 mM 08-503
PDGFRα (PDGFRA) [D842V] TK Km bin. 1 mM Preincubation 08-506
PDGFRβ (PDGFRB) TK Km bin. 1 mM Preincubation 08-158
PDHK2 (PDK2) STK Km bin. 10-140
PDHK4 (PDK4) STK Km bin. 10-125
PDK1 (PDPK1) STK Km bin. 1 mM STK 01-132
PEK (EIF2AK3) STK Km bin. 05-155
PGK (PRKG1) STK Km bin. 01-142
PHKG1 STK Km bin. 02-152
PHKG2 STK Km bin. 02-153
PIM1 STK Km bin. 1 mM Preincubation STK Cell Cycle 02-054
PIM2 STK Km bin. 1 mM Cell Cycle 02-155
PIM3 STK Km bin. 02-156
PKACα (PRKACA) STK Km bin. 1 mM STK 01-127
PKACβ (PRKACB) STK Km bin. 01-128
PKACγ (PRKACG) STK Km bin. 01-129
PKCα (PRKCA) STK Km bin. 1 mM STK 01-133
PKCβ1 (PRKCB1) STK Km bin. 01-134
PKCβ2 (PRKCB2) STK Km bin. 01-165
PKCγ (PRKCG) STK Km bin. 01-137
PKCδ (PRKCD) STK Km bin. Preincubation 01-135
PKCε (PRKCE) STK Km bin. 1 mM Preincubation 01-136
PKCζ (PRKCZ) STK Km bin. Preincubation 01-141
PKCη (PRKCH) STK Km bin. Preincubation 01-138
PKCθ (PRKCQ) STK Km bin. 01-140
PKCι (PRKCI) STK Km bin. 01-139
PKD1 (PRKD1) STK Km bin. Preincubation 02-157
PKD2 (PRKD2) STK Km bin. 1 mM Preincubation STK 02-158
PKD3 (PRKD3) STK Km bin. 02-159
PKN1 STK Km bin. 01-144
PKR (EIF2AK2) STK Km bin. 05-156
PLK1 STK Km bin. 1 mM Cell Cycle 05-157
PLK2 STK Km bin. Cell Cycle 05-158
PLK3 STK Km bin. 1 mM 05-159
PRKX STK Km bin. 01-130
PYK2 (PTK2B) TK Km bin. 1 mM Preincubation TK 08-138
QIK (SNF1LK2) STK Km bin. 1 mM Preincubation 02-129
RAF1 STK 1 mM (Cascade) MAPK (Cascade) 09-125
RET TK Km bin. 1 mM Preincubation 08-159
RET[G691S] TK Km bin. 1 mM Preincubation 08-522
RET[Y791F] TK Km bin. 1 mM Preincubation 08-521
RET[S891A] TK Km bin. 1 mM Preincubation 08-523
RET[M918T] TK Km bin. 1 mM Preincubation 08-508
ROCK1 STK Km bin. 1 mM STK 01-109
ROCK2 STK Km bin. Preincubation 01-110
RON (MST1R) TK Km bin. 1 mM Preincubation 08-152
ROS (ROS1) TK Km bin. 1 mM Preincubation 08-163
RSK1(RPS6KA1) STK Km bin. 1 mM Cell Cycle 01-149
RSK2 (RPS6KA3) STK Km bin. Preincubation 01-150
RSK3 (RPS6KA2) STK Km bin. 1 mM Preincubation 01-151
RSK4 (RPS6KA6) STK Km bin. 1 mM Preincubation 01-152
SGK STK Km bin. 1 mM Preincubation STK 01-158
SGK2 STK Km bin. 01-159
SGK3 (SGKL) STK Km bin. Preincubation 01-160
SIK (SNF1LK) STK Km bin. 1 mM 02-131
skMLCK (MYLK2) STK Km bin. 1 mM Preincubation 02-150
SLK STK Km bin. 07-129
SRC TK Km bin. 1 mM Preincubation TK 08-173
SRM (SRMS) TK Km bin. 1 mM Preincubation 08-174
SRPK1 STK Km bin. 04-160
SRPK2 STK Km bin. 04-161
SYK TK Km bin. 1 mM TK 08-176
TAK1-TAB1 (MAP3K7) STK 1 mM (Cascade) MAPK (Cascade) 09-019
TAOK2 STK Km bin. 07-133
TBK1 STK Km bin. Preincubation 05-115
TEC TK Km bin. 1 mM Preincubation 08-182
TIE2 (TEK) TK Km bin. 1 mM Preincubation TK 08-185
TNIK STK Km bin. 1 mM 07-138
TNK1 TK Km bin. 1 mM 08-104
TRKA (NTRK1) TK Km bin. 1 mM TK 08-186
TRKB (NTRK2) TK Km bin. 1 mM Preincubation 08-187
TRKC (NTRK3) TK Km bin. 1 mM Preincubation 08-197
TSSK1 STK Km bin. 1 mM Preincubation STK 02-364
TSSK2 STK Km bin. 02-165
TSSK3 STK Km bin. 02-166
TXK TK Km bin. 1 mM 08-183
TYK2 TK Km bin. 1 mM 08-147
TYRO3 TK Km bin. 1 mM Preincubation TK 08-109
WNK1 STK Km bin. 05-179
WNK2 STK Km bin. 05-180
WNK3 STK Km bin. 05-181
YES (YES1) TK Km bin. 1 mM Preincubation 08-175
YES (YES1) [T348I] TK Km bin. 1 mM Preincubation 08-533
ZAP70 TK Km bin. 1 mM 08-177