FAQs Archive - Page 27 of 60

Q: How do you mix compounds to achieve equipotent mixtures?

Let’s say we need 50 µL of the mixture, IC 50 of compound A is 1 nM and IC 50 of compound B is 10 nM. In that case we take 25 µL of compound A and 25 µL of compound B. The total of 50 µL is subsequently diluted to generate the dose response curve. Since the compounds are equally effective, 25 µL of compound A can be added to 25 µL of compound B without a ‘dilution effect’.

How do you mix compounds to achieve equipotent mixtures?

Let’s say we need 50 µL of the mixture, IC50 [...]

admin2023-01-26T16:09:59+01:00FAQ SynergyFinder™|

Previous 262728 Next